Preventive option for people at high risk of STIs.
Can help reduce risk of STIs if taken soon after sex.
Choose between script only or medication delivery.
What is DoxyPEP? - It involves taking a prescribed dose of doxycycline after sex to lower your chances of acquiring certain bacterial infections, such as syphilis, chlamydia, and in some cases, gonorrhoea.
Doxycycline 200mg (single dose) taken within 72 hours after unprotected sex can help reduce the risk of certain bacterial STIs.
DoxyPEP is not a substitute for HIV PrEP but can be used alongside it for broader protection.
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Start your DoxyPEP journey - Safely and Effectively
📦 How To Order
1. Select & pay
Select medication delivery or a digital prescription, usable at any registered pharmacy in SA to get your medication
2. Complete assessment
After purchase, you'll be sent a survey. Data about your symptoms & health will be collected for our team to review
3. Get your medication
Based on your choice, get a PDF prescription via email or have your medication delivered (takes 3-5 days)
How does DoxyPEP work?
Doxycycline is an antibiotic that prevents bacteria from multiplying
in the body.
When taken shortly after exposure, it can help stop
the establishment of common bacterial STIs.
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Effectiveness
Studies show DoxyPrEP can reduce the risk of syphilis and chlamydia
by up to 70% in certain populations.
It may also provide partial protection against gonorrhoea, though effectiveness is lower.
It does not protect against HIV, viral STIs (herpes, HPV, hepatitis), or pregnancy.
Who should consider DoxyPEP?
People with multiple partners and inconsistent condom use.
Men who have sex with men (MSM) and other high-risk groups.
People with a recent history of STIs.
Anyone seeking additional protection alongside PrEP.
Why Choose Us?
Confidential & Discreet
Your privacy is protected with secure consultations and discreet delivery.
Expert Medical Care
Licensed healthcare professionals guide you through safe and effective use
Convenient Access
Easy online assessments with medication delivered straight to your door.
Ongoing Support
Follow-ups, testing reminders, and medical advice whenever you need it.
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Need more help?
Book an online consultation with our doctors to assist you in making a decision
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FAQs
No, DoxyPEP can be used independently, but it is most effective when combined with PrEP for HIV prevention.
Possible side effects include nausea, diarrhoea, and sun sensitivity. Taking with food and avoiding direct sunlight can reduce these effects.
Research is ongoing. DoxyPEP should be used under medical supervision to avoid antibiotic resistance and monitor for side effects.
Take 200mg (two tablets) of doxycycline within 72 hours of condomless sex. The sooner, the better.
No. It reduces risk for some STIs but not all. Condoms remain important for full protection against HIV, viral STIs, and pregnancy.
Your privacy is our top priority. All prescriptions, consultations, and deliveries are confidential and discreet.