Low-Dose Naltrexone Program (LDN)

Boost your energy, reduce inflammation and brain fog.

Used off-label to support chronic pain relief, autoimmune conditions, and inflammation - carefully reviewed and dispensed by our medical team.

R 550.00

Initiation Phase (~1mg)*

Request Treatment

Learn How It Works

*Exact dosage and eligibility after clinical consultation

COMPLEMENTARY PROGRAMS

Complement your LDN program with these options

Clinically-backed add-ons our patients pair with their LDN protocol for better results.

Why Patients Choose LDN

Taken at a fraction of the standard dose, LDN works gently with your body to calm inflammation and support everyday wellbeing. Here's why so many patients find it worth trying.

Chronic Pain Relief

Reduces inflammation and helps modulate pain signaling for lasting, everyday relief.

Immune System Support

Helps regulate autoimmune conditions such as fibromyalgia, Crohn's and MS.

Improved Sleep & Mood

Many patients report better sleep quality, brighter mood and noticeably reduced fatigue.

Low Side Effect Profile

Well-tolerated at low doses, with far fewer side effects than standard naltrexone.

How it works

Explore our treatments

You browse our offerings or tell us about your health goals

Submit your details and get a review

Fill out a brief intake form and wait for contact from the medical team

Hear from us - talk to a Clinician

Talk to a clinician about dosing, side effects, or other concerns

Enjoy fast, free shipping

Once orders a approved, orders are delivered to your doorstep

Got Questions?

Frequently Asked Questions

Everything you need to know about this program, from prescriptions to delivery. Still unsure? Our medical team is always happy to help.

Naltrexone is an established medicine traditionally used at higher doses. At very low doses (around 1.5–4.5mg), it is prescribed off-label to gently modulate the immune system and reduce inflammation. This off-label use is well-documented and increasingly recommended for conditions like Long COVID, fibromyalgia, chronic fatigue and autoimmune support.

Yes — LDN is a prescription medication, but we make the process simple. After placing your request, you complete a quick online medical assessment and one of our registered doctors will reach out for a short consult. If LDN is right for you, a prescription is issued and your treatment is prepared, all handled securely online.

Most patients begin with a low starting dose of around 1.5mg per day, which is then gradually titrated upward over several weeks based on how you respond. This slow, steady approach helps your body adjust comfortably and minimises any initial side effects. Your doctor will guide you on the right pace and target dose for you.

LDN is generally very well tolerated. Side effects are mild and uncommon, and usually settle within the first week or two as your body adjusts. The most frequently reported are vivid dreams or lighter sleep and occasionally mild nausea early on. Starting low and titrating slowly keeps these to a minimum, and your doctor is always available if you have concerns.

Everyone responds differently, but most patients begin to notice meaningful improvements in energy, sleep, pain and brain fog within 4 to 8 weeks. Because LDN works gradually by calming inflammation, consistency is key — sticking with your titration schedule gives it the best chance to work. Some people feel subtle changes even sooner.

Once approved, your LDN is carefully compounded and dispensed by a registered pharmacist to the exact strength prescribed for you. It is then delivered discreetly to your chosen address within 2 to 3 working days, in plain, unbranded packaging to protect your privacy. No pharmacy queues, no awkward conversations — just reliable, confidential care.

Still have questions?

Talk to our medical team

Start Feeling Better

Are You Ready to Start Your Journey?

Get assessed by a licensed doctor and start your personalised treatment this week. No pharmacy queues, no waiting rooms - just reliable, confidential care delivered to your door.

Request Tretment

Delivered in 2–3 working days

Licensed Pharmacists

Secure & Confidential

Delivered Discreetly